The role of bone morphogenetic proteins (BMPs) in ovarian function
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Bone morphogenetic proteins (BMPs) have been reported to involve in the ovarian folliculogenesis through interacting with gonadotropin hormones. However, the mechanism of interaction is not clearly understood. The aim of the current study was to demonstrate the mechanism of interaction between BMPs and gonadotropins using different technical approaches. The outcomes of the current study demonstrate that BMPs involves directly and indirectly in regulating follicle development which opens an interesting opportunity to improve fertility and enhance reproductive life.
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Attenuation of Bone Morphogenetic Proteins (BMPs) Signaling Induces Granulosa Cell Sensitivity to Gonadotropins in Female MouseAl Sameira, Sarmed; Palanisamy, Suresh KA; Al-Ali, Ibtisam; Mamotte, Cyril ; McFarlane, James R; Almahbobi, Ghanim (2022)Several lines of evidence support the notion that Bone Morphogenetic Proteins (BMPs) and gonadotropic hormones are major regulators of ovarian follicle development by inducing gonadotropin-mediated steroid hormone production ...
Ovarian follicle development in Booroola sheep exhibiting impaired bone morphogenetic protein signalling pathwayRuoss, Chantelle; Tadros, Amanda; O'Shea, T.; McFarlane, J.; Almahbobi, Ghanim (2009)AbstractThe role of bone morphogenetic proteins (BMPs) in the regulation of ovarian function has been extensively investigated but themechanism of regulation is not well understood. The aim of this study was to investigate ...
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