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    Mathematical modelling of cancer growth

    204892_Jones 2014.pdf (1.084Mb)
    Access Status
    Open access
    Authors
    Jones, Tiffany
    Date
    2014
    Supervisor
    Prof. Lou Caccetta
    Assoc. Prof. Volker Rehbock
    Type
    Thesis
    Award
    PhD
    
    Metadata
    Show full item record
    School
    Department of Mathematics and Statistics
    URI
    http://hdl.handle.net/20.500.11937/2546
    Collection
    • Curtin Theses
    Abstract

    In this thesis we use optimal parameter selection techniques to optimise parameters for mathematical models describing both non-cancerous and cancerous growths. We use computational methods to implement the optimal parameter selection models and discuss our results. We develop a novel model to describe melanoma growth using a set of ordinary differential equations. We incorporate into our model the mutated Braf protein which to our knowledge has not been included in a modelling sense until now.

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