Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk

dc.contributor.author	Galloway, Susan
dc.contributor.supervisor	Dr Le Jian
dc.contributor.supervisor	Prof. John Mamo
dc.date.accessioned	2017-01-30T09:48:50Z
dc.date.available	2017-01-30T09:48:50Z
dc.date.created	2016-08-11T05:35:31Z
dc.date.issued	2015
dc.identifier.uri	http://hdl.handle.net/20.500.11937/330
dc.description.abstract	Alzheimer’s disease beta-amyloid (Aβ) was found in small intestinal enterocytes in association with chylomicrons in wild-type mice. The expression of Aβ was regulated by the availability of substrate from the diet; fasting abolished Aβ, whilst low-fat feeding attenuated Aβ compared to high-fat feeding. This thesis provides novel point of view in context of dietary fat and in particular saturated fatty acids in modulating AD risk.
dc.language	en
dc.publisher	Curtin University
dc.title	Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk
dc.type	Thesis
dcterms.educationLevel	PhD
curtin.department	School of Public Health
curtin.accessStatus	Open access