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dc.contributor.authorLombardo, Daniel Mario
dc.contributor.supervisorDr Alan Payne
dc.date.accessioned2017-01-30T09:48:55Z
dc.date.available2017-01-30T09:48:55Z
dc.date.created2015-06-10T03:08:40Z
dc.date.issued2015
dc.identifier.urihttp://hdl.handle.net/20.500.11937/337
dc.description.abstract

The resolvins are a class of short-lived, naturally occurring compounds with potent anti-inflammatory effects. Using a sequential Sonogashira-Stille reaction, the formal total synthesis of resolvin E1 and the synthesis of a benzene annulated analogue of this compound were completed. The fusion of the benzene ring improves the stability and retains the molecules activity towards the BLT-1 receptor.

dc.languageen
dc.publisherCurtin University
dc.titleSynthesis of a benzene-annulated analogue of resolving E1 and other lipid mediators
dc.typeThesis
dcterms.educationLevelPhD
curtin.departmentDepartment of Chemistry
curtin.accessStatusOpen access


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