Proteinaceous necrotrophic effectors in fungal virulence
MetadataShow full item record
The host–pathogen interface can be considered as a biological battlefront. Molecules produced by both the pathogen and the host are critical factors determining the outcome of the interaction. Recent studies have revealed that an increasing number of necrotrophic fungal pathogens produce small proteinaceous effectors that are able to function as virulence factors. These molecules can cause tissue death in host plants that possess dominant sensitivity genes, leading to subsequent pathogen colonisation. Such effectors are only found in necrotrophic fungi, yet their roles in virulence are poorly understood. However, several recent key studies of necrotrophic effectors from two wheat (Triticum aestivum L.) pathogens, Pyrenophora tritici-repentis (Died.) Drechs. and Stagonospora nodorum (Berk.) Castell. & Germano, have shed light upon how these effector proteins serve to disable the host from the inside out.
A copy of this item may be available from Professor Richard Oliver
Showing items related by title, author, creator and subject.
A comparative hidden Markov model analysis pipeline identifies proteins characteristic of cereal-infecting fungiSperscneider, J.; Gardiner, D.; Taylor, J.; Hane, James; Singh, K.; Manners, J. (2013)Background: Fungal pathogens cause devastating losses in economically important cereal crops by utilisingpathogen proteins to infect host plants. Secreted pathogen proteins are referred to as effectors and have thus farbeen ...
Tan, Kar-Chun; Oliver, Richard; Solomon, P.; Moffat, Caroline (2010)The host–pathogen interface can be considered as a biological battlefront. Molecules produced by both the pathogen and the host are critical factors determining the outcome of the interaction. Recent studies have revealed ...
Transcriptome analysis of the fungal pathogen Fusarium oxysporum f. sp. medicaginis during colonisation of resistant and susceptible Medicago truncatula hosts identifies differential pathogenicity profiles and novel candidate effectorsThatcher, L.; Williams, A.; Garg, G.; Buck, S.; Singh, Karam (2016)Background: Pathogenic members of the Fusarium oxysporum species complex are responsible for vascular wilt disease on many important crops including legumes, where they can be one of the most destructive disease causing ...