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    Molecular Signaling Pathways Involved in the Glucose-Lowering Effect of Teucrium polium

    Access Status
    Fulltext not available
    Embargo Lift Date
    2022-09-12
    Authors
    Mannan, Adnan
    Date
    2017
    Supervisor
    Dr Rima Caccetta
    Prof. Erik Helmerhorst
    Type
    Thesis
    Award
    PhD
    
    Metadata
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    Faculty
    Health
    School
    School of Pharmacy
    URI
    http://hdl.handle.net/20.500.11937/56434
    Collection
    • Curtin Theses
    Abstract

    This thesis demonstrates that an extract of Teucrium polium, a Mediterranean herb with folklore reputation for the treatment of diabetes, does indeed have antidiabetic properties. It promotes insulin secretion from pancreactic beta cells and also has some insulin-like properties. For example, it promotes glucose uptake and storage as glycogen in muscle cells. The plant extract might be an impactful target for future drug discovery efforts for the treatment of type 2 diabetes and related disorders.

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