Enhanced Synthesis and Delivery of Magnesium Oxide Nanoparticles for Reverse Insulin Resistance in Type 2 Diabetes Mellitus
MetadataShow full item record
Type 2 diabetes has emerged to be a major threat to human health. The current study focuses on the formulation of a potential drug to reverse insulin resistance in adipose cells in order to enhance glucose uptake. As magnesium deficiency has proven to increase insulin resistance in diabetic patients, a formulation of magnesium oxide nanoparticles is proposed and proved as a potential drug for reversing insulin resistance and in treating type 2 diabetes.
Showing items related by title, author, creator and subject.
In vivo and in vitro studies of GAD-antibody positive subjects with Type 2 diabetes: A distinct sub-phenotypeO'Gorman, D.; Yousif, O.; Dixon, G.; McQuaid, S.; Murphy, E.; Rahman, Y.; Gasparro, D.; Pacini, G.; Newsholme, Philip; Nolan, J. (2008)The purpose of this study was to determine if immune mechanisms in GAD positive patients' contribute to the pathogenesis of a specific sub-type of Type 2 diabetes. GAD positive (n = 8) and GAD negative (n = 8) subjects ...
Carnagarin, R.; Dharmarajan, Arunasalam; Dass, Crispin (2015)Pigment epithelium-derived factor (PEDF) is an anti-angiogenic serpin associated with insulin resistance in metabolic disorders such as diabetes, metabolic syndrome, obesity and polycystic ovarian syndrome. While the ...
Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: The central role of ROS and nitric oxideNewsholme, Philip; De Bittencourt, P.; O'Hagan, C.; De Vito, G.; Murphy, C.; Krause, M. (2010)It is now widely accepted that hypertension and endothelial dysfunction are associated with an insulin-resistant state and thus with the development of T2DM (Type 2 diabetes mellitus). Insulin signalling is impaired in ...