Genotyping of rota virus causing gastroenteritis in Egyptian children
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Rotavirus (RV) is the major universal early viral infection in childhood gastroenteritis. To identify Rota virus strains causing acute gastroenteritis and its correlation to the disease severity in a sample of Egyptian children in great Cairo. Present study was conducted on 93children presented with acute gastroenteritis during the warm season (March-July).Stool samples were collected from all cases to be tested by PCR for virus detection and typing. Using RT-PCR & PCR test for detection of causative viruses, 53 stool samples were Rota positive. Vomiting, diarrhea and dehydration were found to be significantly higher among Rota virus positive cases (p < 0.005, < 0.005 and < 0.05). The most frequent strains were G3P  13.9%, G2P  11.8%, G4P  7.5%. G1P  6.45%, G12P , G9P  , G9P , G3P  , G4P  and G3P  were also detected. The most frequent strains were G3P , G2P  , G4P . Vomiting, diarrhea and dehydration were found to be higher among Rota virus positive cases.
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