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    Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles

    McMulkin C 2017.pdf (15.57Mb)
    Access Status
    Open access
    Authors
    McMulkin, Calum
    Date
    2017
    Supervisor
    Dr Franca Jones
    Assoc. Prof. Max Massi
    Collection
    • Curtin Theses
    Type
    Thesis
    Education Level
    Ph.D.
    Metadata
    Show full item record
    Abstract

    A series of tetrazoles-containing molecules were investigated for their impact on calcium oxalate monohydrate (COM) crystallisation for the first time. COM is the main constituent of kidney stones, a common pathological mineral in humans. The tetrazole series was found to inhibit the morphology, crystal growth and nucleation of COM directly through selective adsorption or by a complexation mechanism, to varying degrees. Structural trends and which of the tetrazole molecules as crystal growth modifiers were confirmed.

    URI
    http://hdl.handle.net/20.500.11937/65993
    Faculty
    Science and Engineering
    Department
    Chemistry

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