Development of fungal sterol biosynthesis inhibitors as new drug leads for the treatment of Chagas disease

dc.contributor.author	Smith, Erin Nicole
dc.contributor.supervisor	Dr Alan Payne
dc.date.accessioned	2017-01-30T09:52:11Z
dc.date.available	2017-01-30T09:52:11Z
dc.date.created	2015-05-01T06:54:06Z
dc.date.issued	2014
dc.identifier.uri	http://hdl.handle.net/20.500.11937/662
dc.description.abstract	Pyrifenox is a potential drug candidate for the treatment of Chagas disease. A new modular synthesis was established to make pyrifenox and its analogues. These analogues lead to the discovery of compounds that inhibited the causative parasite, Trypanosoma cruzi, at the nanomolar range and the discovery of a new class of compound for the potential treatment of Chagas disease
dc.language	en
dc.publisher	Curtin University
dc.title	Development of fungal sterol biosynthesis inhibitors as new drug leads for the treatment of Chagas disease
dc.type	Thesis
dcterms.educationLevel	PhD
curtin.department	Department of Chemistry
curtin.accessStatus	Open access