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    Electrochemical studies toward proteomic analysis

    199967_Alvarez de Eulate Diaz de San Martin 2014.pdf (16.21Mb)
    Access Status
    Open access
    Authors
    Alvarez de Eulate Diaz de San Martin, Eva Maria
    Date
    2014
    Supervisor
    Dr Debbie S. Silvester
    Prof. Damien W. M. Arrigan
    Type
    Thesis
    Award
    PhD
    
    Metadata
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    School
    Department of Chemistry
    URI
    http://hdl.handle.net/20.500.11937/702
    Collection
    • Curtin Theses
    Abstract

    This thesis provides the basis for a label-free bioanalytical platform using electrochemical analysis at liquid –liquid interfaces. The possibility to detect biomolecules such as proteins in a label-free manner via adsorption and ion-transfer was achieved. Several pre-treatment steps used in proteome analysis, such as protein pre-concentration and digestion, were studied. The results demonstrate the promise of this strategy for the detection and identification of proteins.

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