Luminescent Iridium Tetrazolato Markers for Live Cell Imaging

Abstract

In this research, a series of iridium(III) tetrazolato complexes were synthesised and their photophysical and biological properties investigated. Both the cyclometalated and the ancillary ligands were systematically modified by substitution of functional groups or by increasing the extension of the  conjugation. This approach allowed a more systematic rationalisation of the structure-activity relationship, highlighting how variations in the chemical structure and charge might influence the biological behaviour of these complexes.