Show simple item record

dc.contributor.authorWells, Jason Matthew
dc.contributor.supervisorAlan Payneen_US
dc.date.accessioned2019-09-13T03:33:11Z
dc.date.available2019-09-13T03:33:11Z
dc.date.issued2018en_US
dc.identifier.urihttp://hdl.handle.net/20.500.11937/76286
dc.description.abstract

Tropolones have antimalarial activity with a structure unique compared to current treatments. This study focuses on the development of new methods to prepare tropolones and devise a total synthesis of cordytropolone. A new synthesis of tropolones has been developed using thiophene-1,1-dioxides which are a versatile group of compounds that, to date, have been underutilised in organic synthesis. Substituted thiophene-1,1-dioxides can undergo Diels-Alder reactions with cyclopropenes to form cycloheptatrienes which can be converted to tropolone derivatives.

en_US
dc.publisherCurtin Universityen_US
dc.titleNew Routes to Troponoid Natural Productsen_US
dc.typeThesisen_US
dcterms.educationLevelPhDen_US
curtin.departmentSchool of Molecular and Life Sciencesen_US
curtin.accessStatusOpen accessen_US
curtin.facultyScience and Engineeringen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record