Kafirin purification process development from Sorghum bicolor, Scale-up and application development

Abstract

Kafirin purification process was developed to accommodate both sorghum grain and DDGS with “Quality by Design” (QbD) based approach that assures consistent product quality and facilitate scale-up to commercial scale and technology transfer. Purified kafirin was paired with different plasticizers to develop a screening platform. Kafirin-based biomaterials such as an enteric coat for pharmaceutical drugs, food-grade spray coat to increase shelf life of food materials, films and microparticles were developed and tested.