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    Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth

    Urs RC 2021 Public 2years.pdf (3.290Mb)
    Access Status
    Open access
    Authors
    Urs, Rhea Caroline
    Date
    2021
    Supervisor
    Shannon Simpson
    Andrew Wilson
    Type
    Thesis
    Award
    PhD
    
    Metadata
    Show full item record
    Faculty
    Health Sciences
    School
    School of Allied Health
    URI
    http://hdl.handle.net/20.500.11937/88817
    Collection
    • Curtin Theses
    Abstract

    This research found preterm-born children displayed poor respiratory outcomes, with evidence of increased neutrophilic inflammation and oxidative stress, rather than the eosinophilic profile associated with “typical” childhood asthma. Additionally, metabolomic analysis showed preterm-born individuals have an altered metabolome from those born at term. Together this research provides insight into the contributors of chronic lung disease providing opportunities for early intervention and better lifelong respiratory outcomes in survivors of preterm birth.

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