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dc.contributor.authorGallagher, Ashlee
dc.contributor.supervisorMauro Mocerinoen_US
dc.contributor.supervisorHendra Gunosewoyoen_US

Currently, there is a vital need for new treatment options for the vector-borne, parasitic protozoan diseases, which cause significant morbidity and mortality. This research focused on the synthesis of novel tetrahydroisoquinoline derivatives in order to investigate their anti-parasitic properties. 54 novel derivatives were evaluated, with 3 compounds identified as promising candidates for pre-clinical development for human African trypanosomiasis. The scaffold also showed promise for both Chagas disease and Leishmaniasis, warranting further investigation.

dc.publisherCurtin Universityen_US
dc.titleSynthesis and Biological Evaluation of Anti-Parasitic Compoundsen_US
curtin.departmentSchool of Molecular and Life Sciencesen_US
curtin.accessStatusFulltext not availableen_US
curtin.facultyScience and Engineeringen_US
curtin.contributor.orcidGallagher, Ashlee [0000-0002-8814-357X]en_US

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