The Role of Pigment Epithelium-derived Factor in Breast Cancer Cell Metabolism
| dc.contributor.author | Abooshahab, Raziyeh | |
| dc.contributor.supervisor | Crispin Dass | en_US |
| dc.contributor.supervisor | Hani Al-Salami | en_US |
| dc.date.accessioned | 2025-07-03T05:56:48Z | |
| dc.date.available | 2025-07-03T05:56:48Z | |
| dc.date.issued | 2025 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/98030 | |
| dc.description.abstract |
The thesis investigates the potential of PEDF as a novel regulator of metabolism and metastasis in breast cancer. Findings highlight PEDF's critical role in modulating glucose metabolism, mitochondrial function, and metastatic progression, proposing it as a promising therapeutic target. Additionally, PEDF enhances chemotherapy effectiveness while mitigating drug resistance and side effects, underscoring its value for developing improved metabolism-based breast cancer therapies, pending further validation. | en_US |
| dc.publisher | Curtin University | en_US |
| dc.title | The Role of Pigment Epithelium-derived Factor in Breast Cancer Cell Metabolism | en_US |
| dc.type | Thesis | en_US |
| dcterms.educationLevel | PhD | en_US |
| curtin.department | Curtin Medical School | en_US |
| curtin.accessStatus | Open access | en_US |
| curtin.faculty | Health Sciences | en_US |
| curtin.contributor.orcid | Abooshahab, Raziyeh [0000-0001-7379-0339] | en_US |