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    Coronary computed tomography angiography in coronary artery disease

    171938_47101_303.pdf (802.2Kb)
    Access Status
    Open access
    Authors
    Sun, Zhonghua
    Ng, K.
    Date
    2011
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Sun, Zhonghua and Ng, Kwan-hoong. 2011. Coronary computed tomography angiography in coronary artery disease. World Journal of Cardiology. 3 (9): pp. 303-310.
    Source Title
    World Journal of Cardiology
    DOI
    10.4330/wjc.v3.i9.303.
    ISSN
    1949-8462
    School
    Department of Imaging and Applied Physics
    Remarks

    This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Please refer to the licence to obtain terms for any further reuse or distribution of this work.

    URI
    http://hdl.handle.net/20.500.11937/10235
    Collection
    • Curtin Research Publications
    Abstract

    AIM: To investigate the research directions of coronary computed tomography (CT) angiography in the diagnosis of coronary artery disease (CAD) based on a systematic review of the literature. METHODS: A search of articles on coronary CT angiography in the diagnosis of CAD was performed during a 6-year-period between 2005 and 2010 from five main radiology journals namely, Radiology, American Journal of Roentgenology, European Radiology, European Journal of Radiology and British Journal of Radiology. Analysis of the references was focused on the research directions of coronary CT angiography with regard to the type of studies in terms of diagnostic value, application of dose-reduction strategies and resultant effective radiation doses with use of these techniques. RESULTS: One hundred and forty two studies were identified which met the selection criteria and were included in the analysis. 64-slice CT (single source and dual-source CT) dominated 78% of the coronary CT angiography studies. Prior to 2007, research was focused on the diagnostic value of coronary CT angiography, but since 2008 more attention has been paid to radiation dose reduction. Radiation dose was reported in 64 studies, representing 45% of total studies published in the five radiology journals. Various dose-saving strategies have been implemented and prospective electrocardiography-triggering and high pitch techniques were found to be the most effective approaches for radiation dose reduction, with the corresponding mean effective dose being 3.5 ± 1.9 mSv and 1.7 ± 0.6 mSv, respectively. CONCLUSION: This review shows that the current research in coronary CT angiography has shifted from the previous focus on diagnostic accuracy in CAD to more emphasis on radiation dose reduction.

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