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dc.contributor.authorAsad, Ali Haidar Kasim
dc.contributor.supervisorDr Roger Price
dc.contributor.supervisorDr Suzanne Smith
dc.contributor.supervisorDr Brendan McGann

For thirty years, cyclotron-produced radioisotopes have attracted considerable interest in biomedicine. This thesis describes novel contributions to the production and purification of the positron-emission-tomography (PET) radioisotope copper-61, and its complexation to several bifunctional chelators. Using these technologies we determined the biodistributions of silica nanospheres (Si-NS) in a small-animal model. Si-NS are a promising nanoplatform for delivering diagnostic and therapeutic targeting agents at tumour-cellular level. This research has demonstrated significant potential for PET-radiometal radiophannaceuticals in theranostics.

dc.publisherCurtin University
dc.titleNovel enhancements of cyclotron based production, purification & applications of the PET radionuclide copper-61: Complexation to nanospheres for biomedical imaging
curtin.departmentDepartment of Physics and Astronomy
curtin.accessStatusOpen access

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