The synthesis and biological evaluation of labelled karrikinolides for the elucidation of the mode of action of the seed germination stimulant

Scaffidi, A.; Flematti, G.; Nelson, D.; Dixon, Kingsley; Smith, S.; Ghisalberti, E.

doi:10.1016/j.tet.2010.11.006

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Authors

Scaffidi, A.

Flematti, G.

Nelson, D.

Dixon, Kingsley

Smith, S.

Ghisalberti, E.

Date

2011

Type

Journal Article

Metadata

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Citation

Scaffidi, A. and Flematti, G. and Nelson, D. and Dixon, K. and Smith, S. and Ghisalberti, E. 2011. The synthesis and biological evaluation of labelled karrikinolides for the elucidation of the mode of action of the seed germination stimulant. Tetrahedron. 67 (1): pp. 152-157.

Source Title

Tetrahedron

DOI

10.1016/j.tet.2010.11.006

ISSN

0040-4020

School

Department of Environment and Agriculture

URI

http://hdl.handle.net/20.500.11937/12756

Collection

Curtin Research Publications

Abstract

Karrikins are a novel class of naturally occurring plant growth regulators that promote seed germination among a diverse range of species. Currently little is known about the mechanism by which these compounds overcome seed dormancy and initiate germination. The preparation of various karrikinolide derivatives provides an opportunity to investigate the karrikinolide mode of action at the cellular and molecular level. The first synthesis and biological evaluation of analogues suitable for use in metabolic labelling, affinity chromatography, photoaffinity labelling and NanoSIMS experiments are reported.