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Coronary CT angiography: Diagnostic value and clinical challenges

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Open access
Authors
Sabarudin, Akmal
Sun, Zhonghua
Date
2013
Type
Journal Article

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Sabarudin, Akmal and Sun, Zhonghua. 2013. Coronary CT angiography: Diagnostic value and clinical challenges. World Journal of Cardiology. 5 (12): pp. 473-483.
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World Journal of Cardiology
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This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/). Please refer to the licence to obtain terms for any further reuse or distribution of this work

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Abstract

Coronary computed tomography (CT) angiography has been increasingly used in the diagnosis of coronary artery disease due to improved spatial and temporal resolution with high diagnostic value being reported when compared to invasive coronary angiography. Diagnostic performance of coronary CT angiography has been significantly improved with the technological developments in multislice CT scanners from the early generation of 4-slice CT to the latest 320- slice CT scanners. Despite the promising diagnostic value, coronary CT angiography is still limited in some areas, such as inferior temporal resolution, motion-related artifacts and high false positive results due to severe calcification. The aim of this review is to present an overview of the technical developments of multislice CT and diagnostic value of coronary CT angiography in coronary artery disease based on different generations of multislice CT scanners. Prognostic value of coronary CT angiography in coronary artery disease is also discussed, while limitations and challenges of coronary CT angiography are highlighted.