Polymer-gold nanohybrids with potential use in bimodal MRI/CT: Enhancing the relaxometric properties of Gd(III) complexes

Beija, M.; Chen, Y.Li, Y.; Duong, H.i, Y.eri; Laurent, S.; Elst, L.; Muller, R.; Lowe, Andrew; Davis, T.

doi:10.1039/c2jm34999j

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Authors

Beija, M.

Li, Y.

Duong, H.

Laurent, S.

Elst, L.

Muller, R.

Lowe, Andrew

Davis, T.

Boyer, C.

Date

2012

Type

Journal Article

Metadata

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Citation

Beija, M. and Li, Y. and Duong, H. and Laurent, S. and Elst, L. and Muller, R. and Lowe, A. et al. 2012. Polymer-gold nanohybrids with potential use in bimodal MRI/CT: Enhancing the relaxometric properties of Gd(III) complexes. Journal of Materials Chemistry. 22 (40): pp. 21382-21386.

Source Title

Journal of Materials Chemistry

DOI

10.1039/c2jm34999j

ISSN

0959-9428

School

Nanochemistry Research Institute

URI

http://hdl.handle.net/20.500.11937/14095

Collection

Curtin Research Publications

Abstract

We present a new synthetic strategy to produce Gd(III)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12 000 mM−1 s−1 per particle), indicative of highly efficient CT/MRI CAs.