Polymer-gold nanohybrids with potential use in bimodal MRI/CT: Enhancing the relaxometric properties of Gd(III) complexes
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Authors
Beija, M.
Li, Y.
Duong, H.
Laurent, S.
Elst, L.
Muller, R.
Lowe, Andrew
Davis, T.
Boyer, C.
Date
2012Type
Journal Article
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Beija, M. and Li, Y. and Duong, H. and Laurent, S. and Elst, L. and Muller, R. and Lowe, A. et al. 2012. Polymer-gold nanohybrids with potential use in bimodal MRI/CT: Enhancing the relaxometric properties of Gd(III) complexes. Journal of Materials Chemistry. 22 (40): pp. 21382-21386.
Source Title
Journal of Materials Chemistry
ISSN
School
Nanochemistry Research Institute
Collection
Abstract
We present a new synthetic strategy to produce Gd(III)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12 000 mM−1 s−1 per particle), indicative of highly efficient CT/MRI CAs.