Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Poractant Alfa Versus Beractant for Respiratory Distress Syndrome in Preterm Infants: a Retrospective Cohort Study

    Access Status
    Fulltext not available
    Authors
    Paul, S.
    Rao, S.
    Kohan, R.
    McMichael, J.
    French, N.
    Zhang, Guicheng
    Simmer, K.
    Date
    2013
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Paul, Saritha and Rao, Shripada and Kohan, Rolland and McMichael, Judy and French, Noel and Zhang, Guicheng and Simmer, Karen. 2013. Poractant Alfa Versus Beractant for Respiratory Distress Syndrome in Preterm Infants: a Retrospective Cohort Study. Journal of Paediatrics and Child Health. 49: pp. 839-844.
    Source Title
    Journal of Paediatrics and Child Health
    DOI
    10.1111/jpc.12300
    ISSN
    10344810
    URI
    http://hdl.handle.net/20.500.11937/14685
    Collection
    • Curtin Research Publications
    Abstract

    Aim: Poractant alfa and beractant are the commonly used animal derived surfactants in preterm infants with respiratory distress syndrome. Between 2005 and 2007, poractant alfa and beractant were alternated every month in our neonatal intensive care unit for 27 months. The aim of this study was to compare the outcomes of preterm infants who received poractant alfa versus beractant. Method: Single-centre, retrospective cohort study of inborn preterm infants <32 weeks gestation (23–31+6). Results: Six hundred sixty-four preterm infants (<32 weeks) were born during the study period, of which 415 received surfactant (poractant alfa: 214; beractant: 201). Infants in the poractant alfa group were 2.8 days younger than beractant (27.0 2.3 vs. 27.4 2.3 weeks; P = 0.03). All other baseline characters including Clinical Risk Index for Babies II scores were similar for both groups. No significant differences were found for the following outcomes: death or chronic lung disease (78/212 vs. 59/200; P = 0.28); death (24/214 vs. 15/201, P = 0.24); moderate to severe chronic lung disease (63/212 vs. 46/200; P = 0.45) and moderate to severe disability (20/163 vs. 19/151, P = 0.98) between poractant alfa and beractant, respectively. Conclusions: The results of our study do not support the need for preferential use of poractant alfa or beractant.

    Related items

    Showing items related by title, author, creator and subject.

    • The relationship between early feeding and communication development in preterm and term infants : birth to 12 months
      Smart, Sharon J (2008)
      The relationship between feeding development and early speech production has received increasing interest over the past 30 years. If a relationship between the motor control systems for feeding and communication is present, ...
    • Social and racial inequalities in preterm births in Western Australia, 1984 to 2006
      Langridge, A.; Nassar, N.; Li, Jianghong; Stanley, F. (2010)
      Social and racial inequalities in preterm births in Western Australia, 1984 to 2006 1. Amanda T. Langridge1,*, 2. Natasha Nassar1, 3. Jianghong Li2, 4. Fiona J. Stanley1Article first published online: 21 MAY ...
    • Fixel-based analysis reveals alterations is brain microstructure and macrostructure of preterm-born infants at term equivalent age
      Pannek, K.; Fripp, J.; George, J.; Fiori, S.; Colditz, P.; Boyd, Roslyn; Rose, S. (2018)
      Preterm birth causes significant disruption in ongoing brain development, frequently resulting in adverse neurodevelopmental outcomes. Brain imaging using diffusion MRI may provide valuable insight into microstructural ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.