Activities of Daily Living, Depression, and Quality of Life in Parkinson’s Disease
dc.contributor.author | Lawrence, B. | |
dc.contributor.author | Gasson, Natalie | |
dc.contributor.author | Kane, Robert | |
dc.contributor.author | Bucks, R. | |
dc.contributor.author | Loftus, Andrea | |
dc.date.accessioned | 2017-01-30T11:47:04Z | |
dc.date.available | 2017-01-30T11:47:04Z | |
dc.date.created | 2014-09-05T04:48:05Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Lawrence, B. and Gasson, N. and Kane, R. and Bucks, R. and Loftus, A. 2014. Activities of Daily Living, Depression, and Quality of Life in Parkinson’s Disease. PLoS ONE. 9 (7): Article ID e102294. | |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/14975 | |
dc.identifier.doi | 10.1371/journal.pone.0102294 | |
dc.description.abstract |
This study examined whether activities of daily living (ADL) mediate the relationship between depression and health-related quality of life (HR-QOL) in people with Parkinson’s disease (PD). A cross-sectional, correlational research design examined data from 174 participants who completed the Geriatric Depression Scale (GDS-15), Parkinson’s Disease Questionnaire-39 (PDQ-39), and Unified Parkinson’s Disease Rating Scale-section 2 (UPDRS-section 2 [ADL]). Multiple Regression Analysis (MRA) was used to examine the mediator model. Depression and ADL significantly (p<.001) predicted HR-QOL, and depression significantly (p<.001) predicted ADL. Whilst ADL did not impact on the relationship between depression and HRQOL, there was a significant (p<.001) indirect effect of depression on HR-QOL via ADL, suggesting both direct and indirect (via ADL) effects of depression on HR-QOL. The magnitude of this effect was moderate (R2 = .13). People with PD who report depression also experience greater difficulty completing ADL, which impacts upon their HR-QOL. It is recommended that clinicians adopt a multidisciplinary approach to care by combining pharmacological treatments with psycho/occupational therapy, thereby alleviating the heterogeneous impact of motor and non-motor symptoms on HR-QOL in people with PD. | |
dc.publisher | Public Library of Science | |
dc.title | Activities of Daily Living, Depression, and Quality of Life in Parkinson’s Disease | |
dc.type | Journal Article | |
dcterms.source.volume | 9 | |
dcterms.source.number | 7 | |
dcterms.source.startPage | 1 | |
dcterms.source.endPage | 5 | |
dcterms.source.issn | 1932-6203 | |
dcterms.source.title | PLoS ONE | |
curtin.note |
This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons License | |
curtin.department | School of Psychology | |
curtin.accessStatus | Open access |