Fingerprinting the tertiary structure of electroadsorbed lysozyme at soft interfaces by electrostatic spray ionization mass spectrometry

Alvarez De Eulate, Eva; Qiao, L.; Scanlon, M.; Girault, H.; Arrigan, Damien

doi:10.1039/c4cc05545d

200869_200869.pdf (444.9Kb)

Access Status

Open access

Authors

Alvarez De Eulate, Eva

Qiao, L.

Scanlon, M.

Girault, H.

Arrigan, Damien

Date

2014

Type

Journal Article

Metadata

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Citation

Alvarez De Eulate, E. and Qiao, L. and Scanlon, M. and Girault, H. and Arrigan, D. 2014. Fingerprinting the tertiary structure of electroadsorbed lysozyme at soft interfaces by electrostatic spray ionization mass spectrometry. Chemical Communications. 50 (80): pp. 11829-11832.

Source Title

Chemical Communications

DOI

10.1039/c4cc05545d

ISSN

13597345

School

Department of Applied Chemistry

URI

http://hdl.handle.net/20.500.11937/15093

Collection

Curtin Research Publications

Abstract

Lysozyme can be electrochemically detected after adsorption at an electrified gel–water interface. Ex situ characterization by electrostatic spray ionization mass spectrometry provides insights into the interfacial detection mechanism by allowing changes to the tertiary structure of electroadsorbed lysozyme to be fingerprinted for the first time.