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    Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults

    189436_189436.pdf (153.6Kb)
    Access Status
    Open access
    Authors
    Hirayama, Fumi
    Lee, Andy
    Yasukawa, K.
    Ishihara, Y.
    Shinjo, M.
    Date
    2012
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Hirayama, Fumi and Lee, Andy H. and Yasukawa, Keiji and Ishihara, Yukio and Shinjo, Masaki. 2012. Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults. Journal of Caffeine Research. 2 (4): pp. 176-179.
    Source Title
    Journal of Caffeine Research
    DOI
    10.1089/caf.2012.0029
    ISSN
    2156-5783
    Remarks

    This is a copy of an article published in the Journal of Caffeine Research copyright © 2012 Mary Ann Liebert, Inc.; Journal of Caffeine Research is available online at: http://online.liebertpub.com

    URI
    http://hdl.handle.net/20.500.11937/15932
    Collection
    • Curtin Research Publications
    Abstract

    Background: To investigate the association between caffeine intake and the risk of developing chronic obstructive pulmonary disease (COPD) among Japanese older adults, a case–control study was conducted in central Japan. Methods: A total of 277 patients with COPD aged 50 to 75 years were referred by respiratory physicians, while 340 controls were recruited from the community. All participants had their disease status confirmed by spirometry. Information on habitual caffeine intake, demographic, and lifestyle characteristics was obtained by face-to-face interview using a validated questionnaire. Results: The COPD patients drank more coffee and had a higher mean caffeine intake (311.3, SD 176.2mg/day) than the control group (278.4, SD 188.1 mg/day), p = 0.03. Relative to nondrinkers, the risk of COPD apparently increased for those drinking at least two cups of coffee daily (adjusted odds ratio 1.58, 95% confidence interval [CI] 0.93 to 2.71). Similarly, total caffeine intake was associated with the prevalence of COPD—the adjusted odds ratio being 1.30 (95% CI 1.09 to 2.12) for consuming over 312mg/day when compared to a low intake of less than 184mg/day. Conclusions: The epidemiological evidence suggested a positive association between caffeine intake and the development of COPD in Japanese adults. Further study of the effect of caffeine on lung function and the risk of COPD should be undertaken.

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