The Mechanical Role of the Surface of Articular Cartilage
MetadataShow full item record
Articular cartilage has remarkable biomechanical properties that permit transmitting loads, attenuating dynamic stresses and almost frictionless movements without causing joint pain . Its surface stands for various compressive, shearing and wearing stresses. Disruption of the surface occurs during accidents and physical activities. It consequently leads to the development of osteoarthritis. In this study, the internal microstructure and mechanical function of normal cartilage and the cartilage with the surface disruption have been examined. The chondrocyte shape and mechanical properties of articular cartilage have been found to be altered due to the disruption of the surface.
Showing items related by title, author, creator and subject.
Microstructural and Compositional Features of the Fibrous and Hyaline Cartilage on the Medial Tibial Plateau Imply a Unique Role for the Hopping Locomotion of KangarooHe, Bo; Wu, Jian Ping; Xu, Jiake; Day, Robert; Kirk, Thomas (2013)Hopping provides efficient and energy saving locomotion for kangaroos, but it results in great forces in the knee joints. A previous study has suggested that a unique fibrous cartilage in the central region of the tibial ...
Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartmentsYang, X.; Teguh, D.; Wu, Ping; He, B.; Kirk, T.; Qin, S.; Li, S.; Chen, H.; Xue, W.; Ng, B.; Chim, S.; Tickner, J.; Xu, J. (2015)© 2015 Yang et al. Introduction: Structural alterations in intra-articular and subchondral compartments are hallmarks of osteoarthritis, a degenerative disease that causes pain and disability in the aging population. ...
Elastin fibers display a versatile microfibril network in articular cartilage depending on the mechanical microenvironmentsHe, Bo; Wu, Jianping; Chen, Honghui; Kirk, Thomas; Xu, Jiake (2013)Elastin fibers are major extracellular matrix macromolecules that are critical in maintaining the elasticity and resilience of tissues such as blood vessels, lungs and skins. However, the role of elastin in articular ...