Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview
MetadataShow full item record
Objective: To describe the approach underpinning a national project to estimate the numbers and proportions of cancers occurring in Australia in 2010 that are attributable to modifiable causal factors. Methods: We estimated the population attributable fraction (PAF) (or prevented fraction) of cancers associated with exposure to causal (or preventive) factors using standard formulae. Where possible, we also estimated the potential impact on cancer incidence resulting from changes in prevalence of exposure. Analyses were restricted to factors declared causal by international agencies: tobacco smoke; alcohol; solar radiation; infectious agents; obesity; insufficient physical activity; insufficient intakes of fruits, vegetables and fibre; red and processed meat; menopausal hormone therapy (MHT); oral contraceptive pill (OCP); and insufficient breast feeding. Separately, we estimated numbers of cancers prevented by: aspirin; sunscreen; MHT; and OCP use. We discuss assumptions pertaining to latent periods between exposure and cancer onset, choices of prevalence data and risk estimates, and approaches to sensitivity analyses. Results: Numbers and population attributable fractions of cancer are presented in accompanying papers. Conclusions: This is the first systematic assessment of population attributable fractions of cancer in Australia.
Showing items related by title, author, creator and subject.
Whiteman, D.; Webb, P.; Green, A.; Neale, R.; Fritschi, L.; Bain, C.; Parkin, D.; Wilson, L.; Olsen, C.; Nagle, C.; Pandeya, N.; Jordan, S.; Antonsson, A.; Kendall, B.; Hughes, M.; Ibiebele, T.; Miura, K.; Peters, S.; Carey, Renee (2015)Objective: To estimate the numbers and proportions of cancers occurring in Australia in 2010 attributable to modifiable causal factors. Methods: We estimated the population attributable fraction (PAF) of cancers associated ...
Cancers in Australia attributable to exposure to solar ultraviolet radiation and prevented by regular sunscreen useOlsen, C.; Wilson, L.; Green, A.; Bain, C.; Fritschi, Lin; Neale, R.; Whiteman, D. (2015)© 2015 The Authors. Objectives: To estimate the proportion and numbers of cancers occurring in Australia attributable to solar ultraviolet radiation (UVR) and the proportion and numbers prevented by regular sun protection ...
A protocol for a discrete choice experiment: understanding preferences of patients with cancer towards their cancer care across metropolitan and rural regions in AustraliaWong, S.F.; Norman, Richard; Dunning, T.; Ashley, D.; Lorgelly, P. (2014)Introduction Medical decision-making in oncology is a complicated process and to date there are few studies examining how patients with cancer make choices with respect to different features of their care. It is also ...