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dc.contributor.authorStewart, Louise
dc.contributor.authorHolman, C. D.
dc.contributor.authorSemmens, James
dc.contributor.authorPreen, D.
dc.contributor.authorMai, Q.
dc.contributor.authorHart, R.
dc.date.accessioned2017-01-30T12:06:27Z
dc.date.available2017-01-30T12:06:27Z
dc.date.created2015-07-16T06:21:50Z
dc.date.issued2015
dc.identifier.citationStewart, L. and Holman, C. and Semmens, J. and Preen, D. and Mai, Q. and Hart, R. 2015. Hospital Mental Health Admissions in Women after Unsuccessful Infertility Treatment and In Vitro Fertilization: An Australian Population-Based Cohort Study. PLoS One. 10 (3): e0120076.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/18192
dc.identifier.doi10.1371/journal.pone.0120076
dc.description.abstract

Objective - To examine the association between in vitro fertilization (IVF) and later admission to hospital with a mental health diagnosis in women who remained childless after infertility treatment. Methods - This was a population-based cohort study using linked administrative hospital and registry data. The study population included all women commencing hospital treatment for infertility in Western Australia between the years 1982 and 2002 aged 20–44 years at treatment commencement who did not have a recorded birth by the end of follow-up (15 August 2010) and did not have a hospital mental health admission prior to the first infertility admission (n=6,567). Of these, 2,623 women had IVF and 3,944 did not. We used multivariate Cox regression modeling of mental health admissions and compared women undergoing IVF treatment with women having infertility treatment but not IVF. Results - Over an average of 17 years of follow-up, 411 women in the cohort were admitted to hospital with a mental health diagnosis; 93 who had IVF and 318 who did not. The unadjusted hazard ratio (HR) for a hospital mental health admission comparing women who had IVF with those receiving other infertility treatment was 0.50 (95% confidence interval [CI] 0.40–0.63). After adjustment for age, calendar year and socio-economic status the HR was 0.56 (95% CI 0.44–0.71). Conclusions - IVF treatment is associated with a reduced risk of hospital mental health admissions in women after unsuccessful infertility treatment. This may be explained by the healthy cohort effect.

dc.publisherPublic Library of Science
dc.relation.sponsoredbyhttp://purl.org/au-research/grants/nhmrc/573122
dc.subjecthospital admissions
dc.subjectinfertility
dc.subjectlinked data
dc.subjectpopulation-based cohort study
dc.subjectin vitro fertilization (IVF)
dc.titleHospital Mental Health Admissions in Women after Unsuccessful Infertility Treatment and In Vitro Fertilization: An Australian Population-Based Cohort Study
dc.typeJournal Article
dcterms.source.volume10
dcterms.source.number3
dcterms.source.issn1932-6203
dcterms.source.titlePLoS One
curtin.note

This open access article is distributed under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

curtin.departmentCentre for Population Health Research
curtin.accessStatusOpen access


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