The continual search for ideal biomarkers for mesothelioma: The hurdles
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Malignant pleural mesothelioma (MPM) is an aggressive tumour predominately caused by exposure to asbestos. Asbestos consumption continues to increase worldwide, particularly among developing nations in Asia. Although actual data on mesothelioma incident rates are unavailable from several of the world’s largest asbestos consuming nations including Russia, China and India (1), rates are predicted to surge in Asia reflecting the increased use of asbestos (2). Presently one person dies every four hours from mesothelioma in the United Kingdom.
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Familial aggregation of malignant mesothelioma in former workers and residents of Wittenoom, Western AustraliaDe Klerk, N.; Alfonso, Helman; Olsen, N.; Reid, Alison; Sleith, J.; Palmer, L.; Berry, G.; Musk, A. (2013)Clustering of cases of malignant mesothelioma within families has often been observed, but disentangling genetic and exposure effects has not been done. Former workers and residents exposed to crocidolite at Wittenoom, ...
Robinson, C.; Alfonso, Helman; Woo, S.; Walsh, A.; Olsen, N.; Musk, A.; Robinson, B.; Nowak, A.; Lake, R. (2014)Mesothelioma is principally caused by asbestos and may be preventable because there is a long latent period between exposure and disease development. The most at-risk are a relatively well-defined population who were ...
OccIDEAS: An innovative tool to assess past asbestos exposure in the Australian mesothelioma registryMacFarlane, E.; Benke, G.; Sim, M.; Fritschi, Lin (2012)Malignant mesothelioma is an uncommon but rapidly fatal disease for which the principal aetiological agent is exposure to asbestos. Mesothelioma is of particular significance in Australia where asbestos use was very ...