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    Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial

    Access Status
    Fulltext not available
    Authors
    Ho, S.
    Dhaliwal, Satvinder
    Hills, A.
    Pal, Sebely
    Date
    2013
    Type
    Journal Article
    
    Metadata
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    Citation
    Ho, Suleen S. and Dhaliwal, Satvinder S. and Hills, Andrew P. and Pal, Sebely. 2013. Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial. Inflammation. 36 (3): pp. 625-632.
    Source Title
    Inflammation
    DOI
    10.1007/s10753-012-9584-9
    ISSN
    0360-3997
    URI
    http://hdl.handle.net/20.500.11937/19755
    Collection
    • Curtin Research Publications
    Abstract

    Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or combination exercise on TNF-α and IL-6 compared to no exercise in overweight and obese individuals. TNF-α levels were significantly decreased at week 12 compared to baseline by 20.8 % in the Aerobic group (p = 0.011), 26.9 % in the Resistance group (p = 0.0001), and 32.6 % in the Combination group (p = 0.003). Levels of TNF-α were significantly lower in the Combination compared to the Control group after 12 weeks of exercise training (−22.6 %, p = 0.025) when adjusting for baseline levels. Twelve weeks of moderate-intensity aerobic, resistance, but mainly combination exercise training decreased TNF-α in overweight and obese individuals compared to no exercise. Therefore, combination exercise training may be physiologically relevant in decreasing the risk of developing chronic diseases.

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