The development of MRI-based brain atlases of non-human brains
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This is the peer reviewed version of the following article: Ullmann, J. and Janke, A. and Reutens, D. and Watson, C. 2015. Development of MRI-based brain atlases of non-human brains. Journal of Comparative Neurology. 523: pp. 391-405., which has been published in final form at http://doi.org/10.1002/cne.23678. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving at http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms
Brain atlases are a fundamental resource for neuroscience research. In the past few decades they have undergone a transition from traditional printed histological atlases to digital atlases made up of multiple data sets from multiple modalities, and atlases based on magnetic resonance imaging (MRI) have become widespread. Here we discuss the methods involved in making an MRI brain atlas, including registration of multiple data sets into a model, ontological classification, segmentation of a minimum deformation model, dissemination strategies, and applications of these atlases. Finally, we discuss possible future directions in the development of brain atlases.
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