Cardiopulmonary resuscitation quality and patient survival outcome in cardiac arrest: A systematic review and meta-analysis
MetadataShow full item record
Aim: To conduct a systematic review and meta-analysis to determine whether cardiopulmonary resuscitation (CPR) quality, as indicated by parameters such as chest compression depth, compression rate and compression fraction, is associated with patient survival from cardiac arrest. Methods: Five databases were searched (MEDLINE, Embase, CINAHL, Scopus and Cochrane) as well as the grey literature (MedNar). To satisfy inclusion criteria, studies had to document human cases of in- or out-of hospital cardiac arrest where CPR quality had been recorded using an automated device and linked to patient survival. Where indicated (I2<75%), meta-analysis was undertaken to examine the relationship between individual CPR quality parameters and either survival to hospital discharge (STHD) or return of spontaneous circulation (ROSC). Results: Database searching yielded 8,842 unique citations, resulting in the inclusion of 22 relevant articles. Thirteen were included in the meta-analysis. Chest compression depth was significantly associated with STHD (mean difference (MD) between survivors and non-survivors 2.59. mm, 95% CI: 0.71, 4.47); and with ROSC (MD 0.99. mm, 95% CI: 0.04, 1.93). Within the range of approximately 100-120. compressions per minute (cpm), compression rate was significantly associated with STHD; survivors demonstrated a lower mean compression rate than non-survivors (MD -1.17 cpm, 95% CI: -2.21, -0.14). Compression fraction could not be examined by meta-analysis due to high heterogeneity, however a higher fraction appeared to be associated with survival in cases with a shockable initial rhythm. Conclusions: Chest compression depth and rate were associated with survival outcomes. More studies with consistent reporting of data are required for other quality parameters.
Showing items related by title, author, creator and subject.
Audiovisual feedback device use by health care professionals during CPR: A systematic review and meta-analysis of randomised and non-randomised trialsKirkbright, S.; Finn, Judith; Tohira, Hideo; Bremner, A.; Jacobs, Ian; Celenza, A. (2014)Objectives: A systematic appraisal of the literature to determine if audiovisual feedback devices can improve CPR quality delivered by health care practitioners (HCPs) and/or survival outcomes following cardiac arrest. ...
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infantsSpittle, A.; Orton, J.; Anderson, P.; Boyd, Roslyn; Doyle, L. (2015)Background: Infants born preterm are at increased risk of developing cognitive and motor impairment compared with infants born at term. Early developmental interventions have been provided in the clinical setting with the ...
Tobacco smoking and survival after a prostate cancer diagnosis: A systematic review and meta-analysisDarcey, E.; Boyle, Terry (2018)© 2018 Elsevier Ltd Background: While a number of studies indicate tobacco smoking has a detrimental impact on survival and recurrence after a prostate cancer diagnosis, there has been no quantitative review of this ...