Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream

    Access Status
    Fulltext not available
    Authors
    Mullen, W.
    Edwards, Christine
    Serafini, M.
    Crozier, A.
    Date
    2008
    Type
    Conference Paper
    
    Metadata
    Show full item record
    Citation
    Mullen, W. and Edwards, C. and Serafini, M. and Crozier, A. 2008. Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream, pp. 713-719.
    Source Title
    Journal of Agricultural and Food Chemistry
    DOI
    10.1021/jf072000p
    ISSN
    0021-8561
    School
    School of Public Health
    URI
    http://hdl.handle.net/20.500.11937/20311
    Collection
    • Curtin Research Publications
    Abstract

    Plasma and urine were collected over a 24 h period after the consumption by humans of 200 g of strawberries, containing 222 µmol of pelargonidin-3-O- glucoside, with and without cream. The main metabolite, a pelargonidin-O- glucuronide, reached a peak plasma concentration (C max) of 274 ± 24 nmol/L after 1.1 ± 0.4 h (t max) when only strawberries were ingested. When the strawberries were eaten with cream, the C max was not statistically different but the t max at 2.4 ± 0.5 h was delayed significantly (p < 0.001). The pelargonidin-O-glucuronide, along with smaller quantities of other metabolites, was also excreted in urine in quantities corresponding to ca. 1% of anthocyanin intake. The quantities excreted over the 0 - 24 h collection period were not influenced significantly by cream. However, the 0 - 2 h excretion of anthocyanin metabolites was significantly lower when the strawberries were eaten with cream, whereas the reverse occurred during with the 5 - 8 h excretion period. In keeping with these observations, measurement of plasma paracetamol and breath hydrogen revealed that cream delayed gastric emptying and extended mouth to cecum transit time. © 2008 American Chemical Society.

    Related items

    Showing items related by title, author, creator and subject.

    • Colonic catabolism of dietary phenolic and polyphenolic compounds from Concord grape juice
      Stalmach, A.; Edwards, Christine; Wightman, J.; Crozier, A. (2013)
      After acute ingestion of 350 ml of Concord grape juice, containing 528 µmol of (poly)phenolic compounds, by healthy volunteers, a wide array of phase I and II metabolites were detected in the circulation and excreted in ...
    • Bioavailability and metabolism of orange juice flavanones in humans: Impact of a full-fat yogurt
      Mullen, W.; Archeveque, M.; Edwards, Christine; Matsumoto, H.; Crozier, A. (2008)
      The bioavailability of dietary phytochemicals may be influenced by the food matrix in which they are consumed. In this study the impact of a full-fat yogurt on the bioavailability and metabolism of orange juice flavanones ...
    • A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure
      Ward, Natalie; Tsai, I.; Barden, A.; Van Bockxmeer, F.; Puddey, I.; Hodgson, J.; Croft, K. (2008)
      Arachidonic acid is a major fatty acid that can be metabolized by the cytochrome P450 enzyme to a number of bioactive eicosanoids. A major metabolite of this oxidation is 20-hydroxyeicosatetraenoic acid, which acts as a ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.