Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Australian Cerebral Palsy Child Study: Protocol of a prospective population based study of motor and brain development of preschool aged children with cerebral palsy

    Access Status
    Open access via publisher
    Authors
    Boyd, Roslyn
    Jordan, R.
    Pareezer, L.
    Moodie, A.
    Finn, C.
    Luther, B.
    Arnfield, E.
    Pym, A.
    Craven, A.
    Beall, P.
    Weir, K.
    Kentish, M.
    Wynter, M.
    Ware, R.
    Fahey, M.
    Rawicki, B.
    McKinlay, L.
    Guzzetta, A.
    Date
    2013
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Boyd, R. and Jordan, R. and Pareezer, L. and Moodie, A. and Finn, C. and Luther, B. and Arnfield, E. et al. 2013. Australian Cerebral Palsy Child Study: Protocol of a prospective population based study of motor and brain development of preschool aged children with cerebral palsy. BMC Neurology. 13 (57).
    Source Title
    BMC Neurology
    DOI
    10.1186/1471-2377-13-57
    School
    School of Occupational Therapy and Social Work
    URI
    http://hdl.handle.net/20.500.11937/20676
    Collection
    • Curtin Research Publications
    Abstract

    Background: Cerebral palsy (CP) results from a static brain lesion during pregnancy or early life and remains the most common cause of physical disability in children (1 in 500). While the brain lesion is static, the physical manifestations and medical issues may progress resulting in altered motor patterns. To date, there are no prospective longitudinal studies of CP that follow a birth cohort to track early gross and fine motor development and use Magnetic Resonance Imaging (MRI) to determine the anatomical pattern and likely timing of the brain lesion. Existing studies do not consider treatment costs and outcomes. This study aims to determine the pathway(s) to motor outcome from diagnosis at 18 months corrected age (c.a.) to outcome at 5 years in relation to the nature of the brain lesion (using structural MRI).Methods: This prospective cohort study aims to recruit a total of 240 children diagnosed with CP born in Victoria (birth years 2004 and 2005) and Queensland (birth years 2006–2009). Children can enter the study at any time between 18 months to 5 years of age and will be assessed at 18, 24, 30, 36, 48 and 60 months c.a. Outcomes include gross motor function (GMFM-66 & GMFM-88), Gross Motor Function Classification System (GMFCS); musculoskeletal development (hip displacement, spasticity, muscle contracture), upper limb function (Manual Ability Classification System), communication difficulties using Communication and Symbolic Behaviour Scales-Developmental Profile (CSBS-DP), participation using the Paediatric Evaluation of Disability Inventory (PEDI), parent reported quality of life and classification of medical and allied health resource use and determination of the aetiology of CP using clinical evaluation combined with MRI. The relationship between the pathways to motor outcome and the nature of the brain lesion will be analysed using multiple methods including non-linear modelling, multilevel mixed-effects models and generalised estimating equations. Discussion: This protocol describes a large population-based study of early motor development and brain structure in a representative sample of preschool aged children with CP, using direct clinical assessment. The results of this study will be published in peer reviewed journals and presented at relevant international conferences.

    Related items

    Showing items related by title, author, creator and subject.

    • Cognition and bimanual performance in children with unilateral cerebral palsy: Protocol for a multicentre, cross-sectional study
      Hoare, B.; Ditchfield, M.; Thorley, M.; Wallen, M.; Bracken, J.; Harvey, A.; Elliott, Catherine; Novak, I.; Crichton, A. (2018)
      © 2018 The Author(s). Background: Motor outcomes of children with unilateral cerebral palsy are clearly documented and well understood, yet few studies describe the cognitive functioning in this population, and the ...
    • Relationship between brain lesion characteristics and communication in preschool children with cerebral palsy
      Coleman, A.; Fiori, S.; Weir, K.; Ware, R.; Boyd, Roslyn (2016)
      © 2016Background MRI shows promise as a prognostic tool for clinical findings such as gross motor function in children with cerebral palsy(CP), however the relationship with communication skills requires exploration. Aims ...
    • PREDICT-CP: Study protocol of implementation of comprehensive surveillance to predict outcomes for school-aged children with cerebral palsy
      Boyd, Roslyn; Davies, P.; Ziviani, J.; Trost, S.; Barber, L.; Ware, R.; Rose, S.; Whittingham, K.; Sakzewski, L.; Bell, K.; Carty, C.; Obst, S.; Benfer, K.; Reedman, S.; Edwards, P.; Kentish, M.; Copeland, L.; Weir, K.; Davenport, C.; Brooks, D.; Coulthard, A.; Pelekanos, R.; Guzzetta, A.; Fiori, S.; Wynter, M.; Finn, C.; Burgess, A.; Morris, K.; Walsh, J.; Lloyd, O.; Whitty, J.; Scuffham, P. (2017)
      Objectives: Cerebral palsy (CP) remains the world's most common childhood physical disability with total annual costs of care and lost well-being of $A3.87b. The PREDICT-CP (NHMRC 1077257 Partnership Project: Comprehensive ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.