Kafirin Adsorption on Ion-Exchange resins: Isotherm and Kinetic Studies
MetadataShow full item record
Today kafirin is found to be useful in designing delayed delivery systems and coatings of pharmaceuticals and nutraceuticals where its purity is important and this can be obtained by adsorptive chromatography. This study is the first scientific insight into the isotherm and kinetic studies of kafirin adsorption on anion-and cation-exchange resins for practical applications in preparative scale chromatography. Adsorption isotherms of kafirin were determined for five anion- and two cation-exchange resins in batch systems. Isotherm parameters such as maximum binding capacity and dissociation constant were determined from Langmuir isotherm, and adsorptive capacity and affinity constant from Freundlich isotherm. Langmuir isotherm was found to fit the adsorption equilibrium data well. Batch uptake kinetics for kafirin adsorption on these resins was also carried out and critical parameters including the diffusion coefficient, film mass transfer coefficient, and Biot number for film-pore diffusion model were calculated. Both the isotherm and the kinetic parameters were considered for selection of appropriate resin for kafirin purification. UNOsphere Q (78.26 mg/ml) and Toyopearl SP-650M (57.4 mg/ml) were found to offer better kafirin binding capacities and interaction strength with excellent uptake kinetics under moderate operating conditions. With these adsorbents, film diffusion resistance was found to be major governing factor for adsorption (Bi < 10 and δ < 1). Based on designer objective function, UNOsphere Q was found be best adsorbent for binding of kafirin. The data presented is valuable for designing large scale preparative adsorptive chromatographic kafirin purification systems.
Showing items related by title, author, creator and subject.
Investigation on effects of ion exchangers structure and functional groups on the Re(VII) ions adsorption behavior from aqueous solutionFathi, M.; Nezhadshahmohammadi, F.; Rezai, B.; Alorro, Richard (2018)©, © The Korean Society of Mineral and Energy Resources Engineers (KSMER). Alteration adsorption properties of Re(VII) on two resins with different functional groups and structure, weak base/macroporous and strong base/gel ...
Removal of ZN (II) Metal Ions From Aqueous Solution By Aluminium Oxide (AL2 O3): A Kinetic And Equilibrium StudySen, Tushar; Mei, C. (2012)In this work the adsorptive properties of aluminium oxide in the removal of zinc (Zn2+) from aqueous solution have been studied by laboratory batch adsorption kinetic and equilibrium experiments.The results show that the ...
Cu adsorption behaviours onto chelating resins from glycine-cyanide solutions: Isotherms, kinetics and regeneration studiesDeng, Zixian ; Oraby, Elsayed ; Eksteen, Jacques (2020)© 2019 Elsevier B.V. A method is presented to remove and recover copper from copper-gold glycinate solutions using an iminodiacetic functionalized resin with subsequent regeneration. The adsorption/desorption approach was ...