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dc.contributor.authorPasalich, Maria
dc.contributor.authorSu, Dada
dc.contributor.authorBinns, Colin
dc.contributor.authorLee, Andy
dc.date.accessioned2017-01-30T12:29:48Z
dc.date.available2017-01-30T12:29:48Z
dc.date.created2013-04-11T20:00:26Z
dc.date.issued2013
dc.identifier.citationPasalich, Maria and Su, Dada and Binns, Colin W. and Lee, Andy H. 2013. Reproductive factors for ovarian cancer in southern Chinese women. Journal of Gynecologic Oncology 24 (2): pp. 135-140.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/22179
dc.identifier.doi10.3802/jgo.2013.24.2.135
dc.description.abstract

Objective: To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women. Methods: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, oral contraceptive use and other reproductive factors in a sample of 500 incident ovarian cancer patients and 500 controls (mean age, 59 years). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression models. Results: High parity was inversely associated with ovarian cancer, with an adjusted OR 0.43 (95% CI, 0.30 to 0.62) for women who had given birth to 3 or more children compared to women who had given no more than one birth. Ever use of oral contraceptives was also protective against ovarian cancer; adjusted OR 0.56 (95% CI, 0.40 to 0.78). No association was found for hormone replacement therapy, menopausal status, hysterectomy and family history of ovarian and/or breast cancer. Conclusion: High parity and oral contraceptive use are associated with a lower risk of ovarian cancer in southern Chinese women.

dc.publisherKorean Society of Gynecologic Oncology
dc.subjectParity
dc.subjectOvarian cancer
dc.subjectOral contraceptives
dc.subjectChina
dc.titleReproductive factors for ovarian cancer in southern Chinese women
dc.typeJournal Article
dcterms.source.volume24
dcterms.source.startPage135
dcterms.source.endPage140
dcterms.source.issn2005-0380
dcterms.source.titleJournal of Gynecologic Oncology
curtin.note

This open access article is distributed under the Creative Commons license http://creativecommons.org/licenses/by-nc/3.0/

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curtin.accessStatusOpen access


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