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    Optical coherence elastography: Strain imaging in tissue using optical coherence tomography

    Access Status
    Fulltext not available
    Authors
    Kennedy, B.
    Kennedy, K.
    Ford, Christopher
    McLaughlin, R.
    Bush, M.
    Sampson, D.
    Date
    2012
    Type
    Conference Paper
    
    Metadata
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    Citation
    Kennedy, Brendan F. and Kennedy, Kelsey M. and Ford, Chris and McLaughlin, Robert A. and Bush, Mark B. and Sampson, David D. 2012. Optical coherence elastography: Strain imaging in tissue using optical coherence tomography, in Yanbiao Liao and others (ed), 22nd International Conference on Optical Fiber Sensors, Oct 04 2012. SPIE8421. Beijing, China: Society of Photo-Optical Instrumentation Engineers (SPIE).
    Source Title
    Proceedings of SPIE - The International Society for Optical Engineering
    Source Conference
    22nd International Conference on Optical Fiber Sensors
    DOI
    10.1117/12.975187
    ISSN
    0277786X
    URI
    http://hdl.handle.net/20.500.11937/22659
    Collection
    • Curtin Research Publications
    Abstract

    Optical coherence elastography (OCE) is a strain imaging technique that characterizes the elastic properties of tissues with microscopic resolution in three dimensions. In OCE, the displacement introduced to tissue by mechanical excitation is measured using optical coherence tomography. The local strain is calculated from the spatial derivative of displacement to generate strain images, known as elastograms. To validate elastograms, we compare them to a finite element analysis model of sample deformation. We also present preliminary OCE measurements performed on excised human breast tissue, and demonstrate discrimination of tissue types based on their elastic properties.

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