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    CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study

    132250_Z%20Sun%20Manuscript%20R2.pdf (74.53Kb)
    Access Status
    Open access
    Authors
    Sun, Zhonghua
    Jacobus D.
    Nugrohob, J.
    Adipranotob, J.
    Date
    2009
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Sun, Zhonghua and Jacobus Dimpudus, Franky and Nugroho, Johanes and Adipranotob, Jeffrey Daniel. 2009. CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study. European Journal of Radiology. (In Press)
    Source Title
    European Journal of Radiology
    DOI
    10.1016/j.ejrad.2009.09.007
    ISSN
    0720-048X
    Faculty
    School of Science and Computing
    Faculty of Science and Engineering
    Department of Imaging and Applied Physics
    Remarks

    Copyright © 2009 Elsevier Ireland Ltd All rights reserved.

    URI
    http://hdl.handle.net/20.500.11937/22728
    Collection
    • Curtin Research Publications
    Abstract

    Purpose: The purpose of this study was to investigate the potential value of CT virtual intravascular endoscopy (VIE) in the visualization and assessment of coronary plaques in patients suspected of coronary artery disease.Materials and Methods: 20 (13 men, 7 women, mean age 54 years) consecutive patients with suspected coronary artery disease undergoing 64-slice CT angiography were included in the study. Four main coronary artery branches were assessed with regard to the presence of coronary plaques based on 2D axial, multiplanar reformation, 3D volume rendering and VIE visualizations. The coronary plaques were characterized into calcified, noncalcified and mixed plaques. The intraluminal appearances of these coronary plaques were demonstrated with VIE images and correlated with 2D and 3D images to determine the diagnostic value of VIE for assessment of the plaques.Results: VIE was able to identify and demonstrate the intraluminal appearances of coronary plaques in 18 patients involving 32 coronary artery branches which was shown as an irregularly intraluminal protruding sign in extensively calcified plaques and smooth protruding appearance in noncalcified or focally calcifed plaques. An irregular intraluminal apearance was also noticed in the presence of mixed plaques due to variable components with different CT attenuation contained within the plaques. VIE accurately confirmed the degree of coronary stenosis or occlusion despite presence of heavy calcification.Conclusion: VIE could be used as a complementary tool to conventional CT visualizations for analysis of luminal changes and assessment of disease extent caused by the coronary plaques.

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