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    Occupational exposure to solvents and risk of breast cancer

    235291.pdf (766.0Kb)
    Access Status
    Open access
    Authors
    Glass, D.
    Heyworth, J.
    Thomson, Allyson
    Peters, S.
    Saunders, C.
    Fritschi, Lin
    Date
    2015
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Glass, D. and Heyworth, J. and Thomson, A. and Peters, S. and Saunders, C. and Fritschi, L. 2015. Occupational exposure to solvents and risk of breast cancer. American Journal of Industrial Medicine. 58 (9): pp. 915-922.
    Source Title
    American Journal of Industrial Medicine
    DOI
    10.1002/ajim.22478
    ISSN
    0271-3586
    School
    School of Occupational Therapy and Social Work
    Remarks

    This is the peer reviewed version of the following article: Glass, D. and Heyworth, J. and Thomson, A. and Peters, S. and Saunders, C. and Fritschi, L. 2015. Occupational exposure to solvents and risk of breast cancer. American Journal of Industrial Medicine. 58 (9): pp. 915-922., which has been published in final form at http://doi.org/10.1002/ajim.22478. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving at http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms

    URI
    http://hdl.handle.net/20.500.11937/22816
    Collection
    • Curtin Research Publications
    Abstract

    Background: Occupational exposure to some organic solvents may increase risk of breast cancer. Methods: In a population-based case-control study, 1,205 women diagnosed with primary breast cancer between 2009 and 2011 were drawn from the Western Australian Cancer Registry and matched to 1,789 controls from the electoral roll. Exposure to solvents was determined through telephone interviews using OccIDEAS. Results: About a third of women were occupationally exposed to solvents. Age adjusted breast cancer risks were elevated for women who had been exposed to aliphatic solvents odds ratio (OR) 1.21 (95%CI 0.99-1.48) and aromatic solvents OR 1.21 (95%CI 0.97-1.52). For most solvents the ORs were higher for those diagnosed before menopause. Conclusions: This study suggests that there may be an association between occupational exposure to aliphatic and aromatic solvents and the risk of breast cancer at the low levels of exposure experienced by women in this study.

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