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    A proposal for six sigma integration for large-scale production of penicillin g and subsequent conversion to 6-APA

    Access Status
    Open access via publisher
    Authors
    Nandi, A.
    Pan, S.
    Potumarthi, R.
    Danquah, Michael
    Sarethy, I.
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Nandi, A. and Pan, S. and Potumarthi, R. and Danquah, M. and Sarethy, I. 2014. A proposal for six sigma integration for large-scale production of penicillin G and subsequent conversion to 6-APA. Journal of Analytical Methods in Chemistry. 2014: 413616.
    Source Title
    Journal of Analytical Methods in Chemistry
    DOI
    10.1155/2014/413616
    ISSN
    2090-8865
    School
    Curtin Sarawak
    URI
    http://hdl.handle.net/20.500.11937/23185
    Collection
    • Curtin Research Publications
    Abstract

    Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D). In the current study, we have reviewed and proposed a process for a probable integration of Six Sigma methodology to large-scale production of Penicillin G and its subsequent conversion to 6-aminopenicillanic acid (6-APA). It is anticipated that the important aspects of quality control and quality assurance will highly benefit from the integration of Six Sigma methodology in mass production of Penicillin G and/or its conversion to 6-APA. © 2014 Anirban Nandi et al.

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