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    Using urinary leucocyte esterase tests as an indicator of infection with gonorrhoea or chlamydia in asymptomatic males in a primary health care setting

    Access Status
    Fulltext not available
    Authors
    Rahman, M.
    Beever, W.
    Skov, S.
    Boffa, John
    Date
    2014
    Type
    Journal Article
    
    Metadata
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    Citation
    Rahman, M. and Beever, W. and Skov, S. and Boffa, J. 2014. Using urinary leucocyte esterase tests as an indicator of infection with gonorrhoea or chlamydia in asymptomatic males in a primary health care setting. International Journal of STD and AIDS. 25 (2): pp. 138-144.
    Source Title
    International Journal of STD and AIDS
    DOI
    10.1177/0956462413495670
    ISSN
    0956-4624
    School
    National Drug Research Institute (NDRI)
    URI
    http://hdl.handle.net/20.500.11937/23539
    Collection
    • Curtin Research Publications
    Abstract

    To evaluate a leucocyte esterase test as a predictor of gonorrhoea or chlamydia in asymptomatic Aboriginal males at the Central Australian Aboriginal Congress Male Clinic (Ingkintja), first-void urine samples and clinical information were collected from consecutive asymptomatic males presenting to the Ingkintja in Alice Springs between March 2008 and December 2009. Urine was tested immediately with a leucocyte esterase test dipstick and then by polymerase chain reaction for gonorrhoea and chlamydia. Among the 292 specimens from asymptomatic males, 15.4% were positive for gonorrhoea or chlamydia. In this group, compared with polymerase chain reaction result for gonorrhoea or chlamydia, leucocyte esterase test alone and in combination with age =35 years showed sensitivities of 66.7% and 60%, specificities of 90.7% and 94.7%, positive predictive values of 56.6% and 67.5%, negative predictive values of 93.7% and 92.8% and the area under receiver operating characteristics curve values of 0.79 and 0.85, respectively. Leucocyte esterase tests can reasonably be used as a basis for immediate empirical treatment for gonorrhoea or chlamydia in asymptomatic central Australian Aboriginal men under 35 years of age. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

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