Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Pharmacist intervention for glycaemic control in the community (the RxING study)

    193049_96519_Charrois_BMJOpen_2013.pdf (851.2Kb)
    Access Status
    Open access
    Authors
    Hamarneh, Y.
    Charrois, Theresa
    Lewanczuk, R.
    Tsuyuki, R.
    Date
    2013
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Hamarneh, Yazid N. Al and Charrois, Theresa and Lewanczuk, Richard and Tsuyuki, Ross T. 2013. Pharmacist intervention for glycaemic control in the community (the RxING study). BMJ Open. 3 (9): e003154
    Source Title
    BMJ Open
    DOI
    10.1136/bmjopen-2013-003154
    ISSN
    2044-6055
    Remarks

    This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. http://creativecommons.org/licenses/by-nc/3.0/

    URI
    http://hdl.handle.net/20.500.11937/24648
    Collection
    • Curtin Research Publications
    Abstract

    OBJECTIVE: To determine the effect of a community pharmacist prescribing intervention on glycaemic control in patients with poorly controlled type 2 diabetes. DESIGN: Pragmatic, before–after design. SETTING: 12 community pharmacies in Alberta, Canada. PARTICIPANTS: Type 2 diabetes receiving oral hypoglycaemic medications and with glycated haemoglobin (HbA1c) of 7.5–11%.INTERVENTION: Pharmacists systematically identified potential candidates by inviting patients with type 2 diabetes to test their HbA1c using validated point-of-care technology. Pharmacists prescribed 10 units of insulin glargine at bedtime, adjusted by increments of 1 unit daily to achieve a morning fasting glucose of ≤5.5 mmol/L. The patients were followed up at 2, 4, 8, 14, 20 and 26 weeks. PRIMARY OUTCOME: Change in HbA1c from baseline to week 26. SECONDARY OUTCOMES: Proportion of patients achieving target HbA1c, changes in oral hypoglycaemic agents, quality of life and patient satisfaction, persistence on insulin glargine, number of insulin dosage adjustments per patient and number of hypoglycaemic episodes.RESULTS: We screened 365 patients of whom 111 were eligible. Of those, 100 (90%) were enrolled in the study; all 11 patients who did not consent refused to use insulin. Average age was 64 years (SD 10.4), while average diabetes duration was 10.2 years (SD 7). HbA1c was reduced from 9.1% (SD 1) at baseline to 7.3% (SD 0.9); a change of 1.8% (95% CI 1.4 to 2, p<0.001). Fasting plasma glucose was reduced from 11 (SD 3.3) to 6.9 mmol/L (SD 1.8); a change of 4.1 mmol/L (95% CI of 3.3 to 5, p=0.007). Fifty-one per cent of the patients achieved the target HbA1c of ≤7% at the end of the study.CONCLUSIONS: This is the first completed study of independent prescribing by pharmacists. Our results showed similar improvements in glycaemic control as previous physician-led studies. RxING provides further evidence for the benefit of pharmacist care in diabetes.

    Related items

    Showing items related by title, author, creator and subject.

    • Pharmaceutical care in diabetes mellitus
      Clifford, Rhonda (2004)
      People with diabetes mellitus are more likely to die from cardiovascular causes than those without diabetes, and modifiable risk factors, such as hyperglycaemia, dyslipidaemia and hypertension can be targeted in intervention ...
    • An evaluation of community pharmacy-based services for type 2 diabetes in an Indonesian setting: Patient survey
      Wibowo, Y.; Parsons, R.; Sunderland, B.; Hughes, Jeff (2015)
      Background: Diabetes is an emerging chronic disease in developing countries. Its management in developing countries is mainly hospital/clinic based. The increasing diabetes burden in developing countries provides opportunities ...
    • Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes
      Solimena, Michele; Schulte, A.; Marselli, L.; Ehehalt, F.; Richter, D.; Kleeberg, M.; Mziaut, H.; Knoch, K.; Parnis, J.; Bugliani, M.; Siddiq, A.; Jörns, A.; Burdet, F.; Liechti, R.; Suleiman, M.; Margerie, D.; Syed, F.; Distler, M.; Grützmann, R.; Petretto, E.; Moreno-Moral, A.; Wegbrod, C.; Sönmez, A.; Pfriem, K.; Friedrich, A.; Meinel, J.; Wollheim, C.; Baretton, G.; Scharfmann, R.; Nogoceke, E.; Bonifacio, E.; Sturm, D.; Meyer-Puttlitz, B.; Boggi, U.; Saeger, H.; Filipponi, F.; Lesche, M.; Meda, P.; Dahl, A.; Wigger, L.; Xenarios, I.; Falchi, M.; Thorens, B.; Weitz, J.; Bokvist, K.; Lenzen, S.; Rutter, G.; Froguel, P.; von Bülow, M.; Ibberson, M.; Marchetti, P. (2018)
      © 2017, The Author(s). Aims/hypothesis: Pancreatic islet beta cell failure causes type 2 diabetes in humans. To identify transcriptomic changes in type 2 diabetic islets, the Innovative Medicines Initiative for Diabetes: ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.