Detection and prediction of osteoarthritis in knee and hand joints based on the X-ray image analysis
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Current assessment of osteoarthritis (OA) is primary based on visual grading of joint space narrowing and osteophytes present on radiographs. The approach is observer-dependent, not sensitive enough for the detection of the early stages of OA and time consuming. A promising solution is through fractal analysis of trabecular bone (TB) textures on radiographs. The goal is to develop an automated decision support system for the detection and prediction of OA based on TB texture regions selected on knee and hand radiographs. In this review, we describe our progress towards this development which was conducted in five stages, i.e., (i) development of automated methods for the selection of TB texture regions on knee and hand radiographs (ii), development of fractal signature methods for TB texture analysis, (iii) applications of the methods in the analysis of x-ray images of knees and hands, (iv) development of TB texture classification system, and (v) development of ReadMyXray website for knee x-ray analysis. The results achieved so far are encouraging and it is hoped, that once the system is fully developed and evaluated, it will be used to aid medical practitioners in the decision-making, i.e., in designing OA preventative measures, treatments and monitoring the OA progression.
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A new method to measure trabecular bone texture on hand radiographs: data from the osteoarthritis initiativeWolski, Marcin; Podsiadlo, Pawel; Stachowiak, Gwidon (2014)Purpose: Grading of hand radiographs for joint space narrowing and osteophytes is the traditional method for assessing hand OA. However this assessment can be difficult and inaccurate since the changes of cartilage volume ...
Directional fractal signature methods for trabecular bone texture in hand radiographs: Data from the Osteoarthritis InitiativeWolski, M.; Podsiadlo, P.; Stachowiak, Gwidon (2014)Purpose: To develop directional fractal signature methods for the analysis of trabecular bone (TB) texture in hand radiographs. Problems associated with the small size of hand bones and the orientation of fingers were ...
Differences in trabecular bone texture between knees with and without radiographic osteoarthritis detected by fractal methodsPodsiadlo, Pawel; Dahl, L; Englund, M; Lohmander, L; Stachowiak, Gwidon (2008)Objective: To develop an accurate method for quantifying differences in the trabecular structure in the tibial bone between subjects with and without knee osteoarthritis (OA). Methods: Standard knee radiographs were taken ...