Identifying collagen bundles in the most superficial layer of normal articular cartilage
Access Status
Authors
Date
2009Type
Metadata
Show full item recordCitation
Source Title
Source Conference
ISBN
School
Remarks
© 2009 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Collection
Abstract
Osteoarthritis is characterised by functional failure of synovial joints. It is directly related to degeneration and malfunction of articular cartilage. Earlier studies have reported that normal articular cartilage contains a 3D collagen network integrated with interwoven collagen bundles in the superficial zone. The collagen bundles are critical to the tensile and shearing resistance of articular cartilage. By integrating with the underlying collagen fibres, these collagen bundles also contribute to allow the loading capacity of the normal articular cartilage. The collagen bundles gradually disappear with age and early degradation of articular cartilage. This paper describes a computer image analysis technique developed to identify collagen bundles as an indicator of the healthy status of articular cartilage
Related items
Showing items related by title, author, creator and subject.
-
He, Bo; Wu, Jianping; Chim, Shek Man; Xu, Jiake; Kirk, Brett (2013)Objective: To assess the microstructure of the collagen and elastin fibres in articular cartilage under different natural mechanical loading conditions and determine the relationship between the microstructure of collagen ...
-
He, Bo; Wu, Jian Ping; Xu, Jiake; Day, Robert; Kirk, Thomas (2013)Hopping provides efficient and energy saving locomotion for kangaroos, but it results in great forces in the knee joints. A previous study has suggested that a unique fibrous cartilage in the central region of the tibial ...
-
Duan, Xiaojuan; Wu, Jian Ping; Kirk, Thomas (2013)The structure of the collagen matrix in the most superficial layer of articular cartilage (AC) is particularly critical to the wear and tensile resistance of AC. Disruption of the collagen network leads to rapid wear of ...