Increased hospital costs associated with red blood cell transfusion
MetadataShow full item record
Background - Red blood cell (RBC) transfusion is independently associated in a dose-dependent manner with increased intensive care unit stay, total hospital length of stay, and hospital-acquired complications. Since little is known of the cost of these transfusion-associated adverse outcomes our aim was to determine the total hospital cost associated with RBC transfusion and to assess any dose-dependent relationship. Study Design and Methods - A retrospective cohort study of all multiday acute care inpatients discharged from a five hospital health service in Western Australia between July 2011 and June 2012 was conducted. Main outcome measures were incidence of RBC transfusion and mean inpatient hospital costs. Results - Of 89,996 multiday, acute care inpatient discharges, 4805 (5.3%) were transfused at least 1 unit of RBCs. After potential confounders were adjusted for, the mean inpatient cost was 1.83 times higher in the transfused group compared with the nontransfused group (95% confidence interval, 1.78-1.89; p < 0.001). The estimated total hospital-associated cost of RBC transfusion in this study was AUD $77 million (US $72 million), representing 7.8% of total hospital expenditure on acute care inpatients. There was a significant dose-dependent association between the number of RBC units transfused and increased costs after adjusting for confounders. Conclusion - RBC transfusions were independently associated with significantly higher hospital costs. The financial implication to hospital budgets will assist in prioritizing areas to reduce the rate of RBC transfusions and in implementing patient blood management programs.
Showing items related by title, author, creator and subject.
Hofmann, Axel; Farmer, Shannon; Towler, Simon (2012)Purpose of review: Evidence-based patient blood management (PBM) is aimed at achieving better patient outcomes by relying on a patient's own blood rather than on donor blood. This review covers the rationale behind PBM, ...
Impact of a patient blood management program and an outpatient anemia management protocol on red cell transfusions in oncology inpatients and outpatientsGross, I.; Gross, I.; Trentino, K.; Andreescu, A.; Pierson, R.; Maietta, R.; Farmer, Shannon; Farmer, S. (2016)© AlphaMed Press 2016. Background. Patient blood management (PBM) programs are associated with reduced transfusion usage, reduced hospital costs, and improved patient outcomes.The application of PBM principles in patients ...
The IRONMAN trial: a protocol for a multicentre randomised placebo-controlled trial of intravenous iron in intensive care unit patients with anaemiaLitton, E.; Baker, S.; Erber, W.; French, C.; Ferrier, J.; Hawkins, D.; Higgins, A.; Hofmann, Axel; De Keulenaer, B.; Farmer, Shannon; McMorrow, J.; Olynyk, John; Richards, T.; Towler, Simon; Webb, S. (2014)Background: Allogeneic red blood cell (RBC) transfusion is associated with significant increases in mortality and major morbidity in patients admitted to the intensive care unit, and the blood supplies it requires are an ...