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    A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection

    196024_105106_652520.pdf (2.998Mb)
    Access Status
    Open access
    Authors
    Wan Ab Naim, Naimah
    Balan Ganesan, Poo
    Sun, Zhonghua
    Chee, Kok
    Hashim, Shahrul
    Lim, Einly
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Wan Ab Naim, Naimah and Balan Ganesan, Poo and Sun, Zhonghua and Chee, Kok and Hashim, Shahrul and Lim, Einly. 2014. A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection. The Scientific World Journal. Article ID 652520 (12 p.).
    Source Title
    The Scientific World Journal
    DOI
    10.1155/2014/652520
    ISSN
    1537-744X
    Remarks

    This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ Please refer to the licence to obtain terms for any further reuse or distribution of this work.

    URI
    http://hdl.handle.net/20.500.11937/25696
    Collection
    • Curtin Research Publications
    Abstract

    Aortic dissection, characterized by separation of the layers of the aortic wall, poses a significant challenge for clinicians. While type A aortic dissection patients are normally managed using surgical treatment, optimal treatment strategy for type B aortic dissection remains controversial and requires further evaluation. Although aortic diameter measured by CT angiography has been clinically used as a guideline to predict dilation in aortic dissection, hemodynamic parameters (e.g., pressure and wall shear stress), geometrical factors, and composition of the aorta wall are known to substantially affect disease progression. Due to the limitations of cardiac imaging modalities, numerical simulations have been widely used for the prediction of disease progression and therapeutic outcomes, by providing detailed insights into the hemodynamics. This paper presents a comprehensive review of the existing numerical models developed to investigate reasons behind tear initiation and progression, as well as the effectiveness of various treatment strategies, particularly the stent graft treatment.

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