Show simple item record

dc.contributor.authorChiang, Y.
dc.contributor.authorChao, D.
dc.contributor.authorChu, Shu-Fen
dc.contributor.authorLin, H.
dc.contributor.authorHuang, S.
dc.contributor.authorYeh, Y.
dc.contributor.authorLui, T.
dc.contributor.authorBinns, Colin
dc.contributor.authorChiu, W.
dc.date.accessioned2017-01-30T12:52:04Z
dc.date.available2017-01-30T12:52:04Z
dc.date.created2012-03-26T20:01:23Z
dc.date.issued2012
dc.identifier.citationChiang, Yung-Hsiao and Chao, Dan-Ping and Chu, Shu-Fen and Lin, Hui-Wen and Huang, Shih-Yi and Yeh, Yi-Shian and Lui, Tai-Ngar and Binns, Colin W. and Chiu, Wen-Ta. 2012. Early Enteral Nutrition and Clinical Outcomes of Severe Traumatic Brain Injury Patients in Acute Stage: A Multi-Center Cohort Study. Journal of Neurotrauma. 29 (1): pp. 75-80.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/26162
dc.identifier.doi10.1089/neu.2011.1801
dc.description.abstract

Guidelines for patients with severe traumatic brain injury (sTBI) published in 2007 recommend providing early nutrition after trauma. Early enteral nutrition (EN) started within 48 h post-injury reduces clinical malnutrition, prevents bacterial translocation from the gastrointestinal tract, and improves outcome in sTBI patients sustaining hypermetabolism and hypercatabolism. The aim of this study was to examine the effect of early EN support on survival rate, Glasgow Coma Scale (GCS) score, and clinical outcome of sTBI patients. Medical records of sTBI patients with GCS scores 4–8 were recruited from 18 hospitals in Taiwan, excluding patients with GCS scores ≤3. During 2002–2010, data from 145 EN patients receiving appropriate calories and nutrients within 48 h post-trauma were collected and compared with 152 non-EN controls matched for gender, age, body weight, initial GCS score, and operative status. The EN patients had a greater survival rate and GCS score on the 7th day in the intensive care unit (ICU), and a better outcome at 1 month post-injury. After adjusting for age, gender, initial GCS score, and recruitment period, the non-EN patients had a hazard ratio of 14.63 (95% CI 8.58–24.91) compared with EN patients. The GCS score during the first 7 ICU days was significantly improved among EN patients with GCS scores of 6–8 compared with EN patients with GCS scores of 4–5 and non-EN patients with GCS scores of 6–8. This finding demonstrates that EN within 48 h post-injury is associated with better survival, GCS recovery, and outcome among sTBI patients, particularly in those with a GCS score of 6–8.

dc.publisherMary Ann Liebert Inc
dc.titleEarly Enteral Nutrition and Clinical Outcomes of Severe Traumatic Brain Injury Patients in Acute Stage: A Multi-Center Cohort Study
dc.typeJournal Article
dcterms.source.volume29
dcterms.source.startPage75
dcterms.source.endPage80
dcterms.source.issn0897-7151
dcterms.source.titleJournal of Neurotrauma
curtin.departmentSchool of Public Health
curtin.accessStatusFulltext not available


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record