Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Numerical methods for estimating effective diffusion coefficients of three-dimensional drug delivery systems

    Access Status
    Fulltext not available
    Authors
    Mohd-Mahali, S.
    Wang, S.
    Lou, Xia
    Pintowantoro, S.
    Date
    2012
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Mohd-Mahali, S. and Wang, S. and Lou, X. and Pintowantoro, S. 2012. Numerical methods for estimating effective diffusion coefficients of three-dimensional drug delivery systems. Numerical Algebra, Control and Optimization. 2 (2): pp. 377-393.
    Source Title
    Numerical Algebra, Control and Optimization
    DOI
    10.3934/naco.2012.2.377
    ISSN
    2155-3289
    School
    Department of Chemical Engineering
    URI
    http://hdl.handle.net/20.500.11937/26502
    Collection
    • Curtin Research Publications
    Abstract

    This paper presents a numerical technique in three dimensions for estimating effective diffusion coefficients of drug release devices in rotating and flow-through fluid systems. We first formulate the drug release problems as diffusion equation systems with unknown effective diffusion coefficients. We then develop a numerical technique for estimating the unknown coefficients based on a nonlinear least-squares method and a finite volume discretization scheme for the 3D diffusion equations. Numerical experiments have been performed using experimental data and the numerical results are presented to show that our methods give accurate diffusivity estimations for the test problems.

    Related items

    Showing items related by title, author, creator and subject.

    • Determination of effective diffusion coefficients of drug delivery devices by a state observer approach
      Mahali, S.; Wang, S.; Lou, Xia (2011)
      In this paper we present a state observer approach for the estimation of effective diffusion coefficients of a drug delivery device. In this approach, we construct estimators for the unknown effective diffusion coefficients ...
    • On the critical factors for estimating the pit stability product under a salt film
      Wang, Ke ; Salasi, Mobin ; Bakhtiari, Sam ; Iannuzzi, Mariano (2021)
      The pit stability product of 316L stainless steel (SS) under a salt film was examined by experimental techniques, analytical methods, and numerical modeling. Both analytical and numerical results suggested that electromigration ...
    • Mathematical models for estimating effective diffusion parameters of spherical drug delivery devices
      Wang, S.; Mahali, S.; McGuiness, Andrea; Lou, Xia (2010)
      Mathematical modeling of drug delivery is of increasing academic and industrial importance in manyaspects. In this paper, we propose an optimization approach for the estimation of the parameters characterizing the diffusion ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.