Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Cognitive impairment among Indonesia HIV naïve patients

    235035_235035.pdf (271.8Kb)
    Access Status
    Open access
    Authors
    Estiasari, R.
    Imran, J.
    Lastri, D.
    Prawiro-Hardjo, P.
    Price, Patricia
    Date
    2015
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Estiasari, R. and Imran, J. and Lastri, D. and Prawiro-Hardjo, P. and Price, P. 2015. Cognitive impairment among Indonesia HIV naïve patients. Neurology Asia. 20 (2): pp. 155-160.
    Source Title
    Neurology Asia
    Additional URLs
    http://www.neurology-asia.org/articles/neuroasia-2015-20(2)-155.pdf
    ISSN
    1823-6138
    School
    School of Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/26612
    Collection
    • Curtin Research Publications
    Abstract

    Background: Antiretroviral treatment (ART) can decreased the incidence of HIV dementia, but milder cognitive impairment may not resolve when patients receive ART. In Indonesia, cognitive screening of HIV patients is not routinely performed before starting ART. Here we assess cognitive impairment in ART- naïve HIV patients beginning treatment in Jakarta. Methods: This is a cross sectional study with inclusion criteria: HIV positive, ART naïve, CD4 T-cells below 200 cells/uL, Karnofsky Performance Score (KPS) above 70. HIV-associated neurocognitive disorder (HAND) was defined by performance at least 1 Standard Deviation (SD) below the mean of demographically adjusted normative scores in at least two cognitive areas. Results: We studied 82 subjects with median (range) age 31 (19-48) years. Fifty six subjects (68%) were males. HAND was found in 42 subjects (51%). Eight subjects (19%) had impairment in 4 domains, 15 subjects (36%) in 3 and 19 (45%) in 2. The most common domain affected was memory (63%). Conclusion: Our results show the prevalence of HAND is high among HIV naïve patients in Jakarta. This establishes the need for screening of cognitive function before initiating ART.

    Related items

    Showing items related by title, author, creator and subject.

    • An Experimental Simulation of Heat Effects on Cognition and Workload of Surgical Team Members
      Ward, Mary K. ; Yam, C.M.H.; Palejwala, Z.; Wallman, K.; Taggart, S.M.; Wood, F.M.; Parker, Sharon (2021)
      Objective: To isolate heat exposure as a cause of cognitive impairment and increased subjective workload in burns surgical teams. Summary of Background Data: Raising ambient temperature of the operating room can improve ...
    • Early developmental intervention programmes post-hospital discharge to prevent motor and cognitive impairments in preterm infants
      Spittle, A.; Orton, J.; Anderson, P.; Boyd, Roslyn; Doyle, L. (2012)
      Background: Infants born preterm are at increased risk of developing cognitive and motor impairments compared with infants born at term. Early developmental interventions have been used in the clinical setting with the ...
    • Lack of reliable evidence for a distinctive ε4-related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian Imaging, Biomarkers and Lifestyle Study
      Foster, Jonathan; Albrecht, Matthew; Savage, Greg; Lautenschlager, Nicola T.; Ellis, Kathryn A.; Maruff, Paul; Szoeke, Cassandra; Taddei, Kevin; Martins, Ralph; Masters, Colin L.; Ames, David (2013)
      Individuals who carry the apolipoprotein E ε4 polymorphism have an increased risk of late-onset Alzheimer’s disease. However, because possession of the ε4 allele confers an increased risk for the diagnosis of dementia, ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.